Title : Mislocalization of TORC1 to Lysosomes Caused by KIF11 Inhibition Leads to Aberrant TORC1 Activity.

Pub. Date : 2020 Aug 31

PMID : 32759469






1 Functional Relationships(s)
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1 While the growth factors like insulin initiate a signaling cascade to induce conformational changes in the mechanistic target of rapamycin complex 1 (mTORC1), amino acids cause the complex to localize to the site of activation, the lysosome. Sirolimus insulin Homo sapiens