Title : Based on the Virtual Screening of Multiple Pharmacophores, Docking and Molecular Dynamics Simulation Approaches toward the Discovery of Novel HPPD Inhibitors.

Pub. Date : 2020 Aug 3

PMID : 32756361






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an iron-dependent non-heme oxygenase involved in the catabolic pathway of tyrosine, which is an important enzyme in the transformation of 4-hydroxyphenylpyruvic acid to homogentisic acid, and thus being considered as herbicide target. Tyrosine 4-hydroxyphenylpyruvate dioxygenase Homo sapiens
2 4-Hydroxyphenylpyruvate dioxygenase (HPPD) is an iron-dependent non-heme oxygenase involved in the catabolic pathway of tyrosine, which is an important enzyme in the transformation of 4-hydroxyphenylpyruvic acid to homogentisic acid, and thus being considered as herbicide target. Tyrosine 4-hydroxyphenylpyruvate dioxygenase Homo sapiens