Pub. Date : 2020 Jul 31
PMID : 32751912
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | More than half a decade ago, it has been shown that the inflammasome adaptor molecule, ASC requires tyrosine phosphorylation to allow effective inflammasome assembly and sustained IL-1beta/IL-18 release. | Tyrosine | interleukin 18 | Homo sapiens |
| 2 | In the subsequent years, it was reported that activation of the inflammasome receptor molecule, NLRP3, is modulated via tyrosine phosphorylation as well, and that NLRP3 de-phosphorylation at specific tyrosine residues was required for inflammasome assembly and sustained IL-1beta/IL-18 release. | Tyrosine | interleukin 18 | Homo sapiens |