Title : Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.

Pub. Date : 2020 Aug

PMID : 32742408






1 Functional Relationships(s)
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1 In conclusion, the findings of the present study provided evidence to suggest that vitamin D3 may prevent articular cartilage degeneration and osteoarthritic disease progression by inhibiting the expression levels of MMP-3, MMP-13, ADAMTS-4 and ADAMTS-5 through suppressing the Wnt/beta-catenin signaling pathway. Cholecalciferol ADAM metallopeptidase with thrombospondin type 1 motif 4 Homo sapiens