Title : A Study of the Effect of Cyclosporine on Fevipiprant Pharmacokinetics and its Absolute Bioavailability Using an Intravenous Microdose Approach.

Pub. Date : 2020 Oct

PMID : 32739890






1 Functional Relationships(s)
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1 This drug-drug interaction (DDI) study determined the effect of cyclosporine, an inhibitor of OATP1B3 and P-gp, on the pharmacokinetics (PK) of fevipiprant, an oral, highly selective, competitive antagonist of the prostaglandin D2 receptor 2 and a substrate of the two transporters. Cyclosporine solute carrier organic anion transporter family member 1B3 Homo sapiens