Title : Evaluation of acacetin inhibition potential against cytochrome P450 in vitro and in vivo.

Pub. Date : 2020 Sep 25

PMID : 32738202






1 Functional Relationships(s)
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1 The aim of the present study was to investigate the effects of acacetin on the activities of the cytochrome P450 family members CYP1A2, CYP2B1, CYP2C11, CYP2D1, CYP2E1, and CYP3A2 in rat liver microsomes in vitro and rats in vivo to evaluate potential herb-drug interactions by using a cocktail approach. acacetin cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus