Title : Autophagy-related neurotoxicity is mediated via AHR and CAR in mouse neurons exposed to DDE.

Pub. Date : 2020 Nov 10

PMID : 32721735






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Selective antagonists of the receptors, including alpha-naphthoflavone, CH223191, and CINPA 1, inhibited p,p"-DDE- and o,p"-DDE-induced LDH release and caspase-3 activity, while specific siRNAs (Ahr and Car siRNA) reduced the levels of p,p"-DDE- and o,p"-DDE-induced autophagosome formation. alpha-naphthoflavone aryl hydrocarbon receptor Homo sapiens