Title : Combination of pomegranate extract and curcumin ameliorates thioacetamide-induced liver fibrosis in rats: impact on TGF-β/Smad3 and NF-κB signaling pathways.

Pub. Date : 2020 Oct

PMID : 32718261






1 Functional Relationships(s)
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1 The results indicated that PE and/or curcumin attenuated TAA-induced liver fibrogenesis, as evidenced by significant improvement in the liver function tests (AST, ALT, ALP, and albumin), oxidative stress biomarkers (MDA, SOD, and GSH), and inflammatory biomarkers (NF-kB, TNF-alpha, IL-1beta, iNOS, TGF-beta, and MPO), compared to TAA group. Curcumin nitric oxide synthase 2 Rattus norvegicus