Title : Type III intermediate filaments as targets and effectors of electrophiles and oxidants.

Pub. Date : 2020 Sep

PMID : 32711378






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 The type III IFs, vimentin, desmin, peripherin and glial fibrillary acidic protein (GFAP), are targets for diverse modifications by oxidants and electrophiles, for which their conserved cysteine residue emerges as a hot spot. Cysteine vimentin Homo sapiens
2 We previously proposed that cysteine residues of vimentin and GFAP act as sensors for oxidative and electrophilic stress, and as hinges influencing filament assembly. Cysteine vimentin Homo sapiens