Title : Combined administration of SHP2 inhibitor SHP099 and the α7nAChR agonist PNU282987 protect mice against DSS‑induced colitis.

Pub. Date : 2020 Sep

PMID : 32705242






2 Functional Relationships(s)
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1 Combined administration of SHP2 inhibitor SHP099 and the alpha7nAChR agonist PNU282987 protect mice against DSS-induced colitis. PNU-282987 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 The present study aimed to evaluate the protective effects of PNU282987 and SHP099, which are a selective agonist of alpha7nAChR and an SHP2 inhibitor, respectively, in dextran sulfate sodium (DSS)-induced colitis in mice. PNU-282987 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus