Title : AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer.

Pub. Date : 2020 Jul 23

PMID : 32703218






2 Functional Relationships(s)
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1 On the contrary, the activation of AMPK by metformin (Met) or 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) could overcome the KRAS-induced resistance to the anti-EGFR antibody in vivo and in vitro. Metformin epidermal growth factor receptor Homo sapiens
2 On the contrary, the activation of AMPK by metformin (Met) or 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) could overcome the KRAS-induced resistance to the anti-EGFR antibody in vivo and in vitro. Metformin epidermal growth factor receptor Homo sapiens