Pub. Date : 2021 Jan
PMID : 32686977
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An in vitro approach to simulate the process of 5-fluorouracil degradation with dihydropyrimidine dehydrogenase: the process in accordance to the first-order kinetic reaction. | Fluorouracil | dihydropyrimidine dehydrogenase | Homo sapiens |
| 2 | The effects of initial 5-FU concentrations and temperatures on DPD activities were investigated as well.The degradation process followed the first-order kinetic reaction (r2>0.98). | Fluorouracil | dihydropyrimidine dehydrogenase | Homo sapiens |
| 3 | The degradation process of 5-FU in patients" whole blood in vitro was consistent with it after mixing 5-FU with blank whole blood matrix.In conclusion, mixing 5-FU with blank matrix can simulate the process of 5-FU degradation with DPD. | Fluorouracil | dihydropyrimidine dehydrogenase | Homo sapiens |
| 4 | The degradation process of 5-FU in patients" whole blood in vitro was consistent with it after mixing 5-FU with blank whole blood matrix.In conclusion, mixing 5-FU with blank matrix can simulate the process of 5-FU degradation with DPD. | Fluorouracil | dihydropyrimidine dehydrogenase | Homo sapiens |
| 5 | The degradation process of 5-FU in patients" whole blood in vitro was consistent with it after mixing 5-FU with blank whole blood matrix.In conclusion, mixing 5-FU with blank matrix can simulate the process of 5-FU degradation with DPD. | Fluorouracil | dihydropyrimidine dehydrogenase | Homo sapiens |
| 6 | The degradation process of 5-FU in patients" whole blood in vitro was consistent with it after mixing 5-FU with blank whole blood matrix.In conclusion, mixing 5-FU with blank matrix can simulate the process of 5-FU degradation with DPD. | Fluorouracil | dihydropyrimidine dehydrogenase | Homo sapiens |