Pub. Date : 2020 Dec
PMID : 32666123
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PURPOSE: Drug-drug interaction (DDI) potentials of lusutrombopag, a thrombopoietin receptor agonist, on the activity of cytochrome P450 (CYP) 3A and of cyclosporine, which inhibits P-glycoprotein and breast cancer resistance protein, on lusutrombopag pharmacokinetics were assessed via clinical studies and physiologically based pharmacokinetic (PBPK) modeling. | lusutrombopag | ATP binding cassette subfamily B member 1 | Homo sapiens |