Title : Osteoblast-Osteoclast Coculture Amplifies Inhibitory Effects of FG-4592 on Human Osteoclastogenesis and Reduces Bone Resorption.

Pub. Date : 2020 Jul

PMID : 32666021






1 Functional Relationships(s)
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1 The PHD enzyme inhibitor FG-4592 stabilized HIF protein and stimulated osteoclast-mediated bone resorption, but inhibited differentiation of human CD14+ monocytes into osteoclasts. roxadustat CD14 molecule Homo sapiens