Protein Name CD14 molecule
Organism Homo sapiens
Gene ID 929
Gene Symbol

CD14

UniProt P08571 (CD14_HUMAN)
Relationships Total Number of functionally related compound(s) : 797
Total Number of Articles : 1155
Description

CD14 molecule

Gene Summary

The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]

synonyms
  • monocyte differentiation antigen CD14
  • myeloid cell-specific leucine-rich glycoprotein
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Properties