Title : Transcriptional and posttranscriptional regulation of CSF-1 gene expression in human monocytes.

Pub. Date : 1988 Sep

PMID : 3265472






4 Functional Relationships(s)
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1 TPA-treated monocytes exposed to actinomycin D further demonstrated that the half-life of the CSF-1 mRNA is 0.9 h. The results also demonstrated that the protein synthesis inhibitor, cycloheximide (CHX), increases CSF-1 mRNA levels in both resting and TPA-treated monocytes. Cycloheximide colony stimulating factor 1 Homo sapiens
2 TPA-treated monocytes exposed to actinomycin D further demonstrated that the half-life of the CSF-1 mRNA is 0.9 h. The results also demonstrated that the protein synthesis inhibitor, cycloheximide (CHX), increases CSF-1 mRNA levels in both resting and TPA-treated monocytes. Cycloheximide colony stimulating factor 1 Homo sapiens
3 TPA-treated monocytes exposed to actinomycin D further demonstrated that the half-life of the CSF-1 mRNA is 0.9 h. The results also demonstrated that the protein synthesis inhibitor, cycloheximide (CHX), increases CSF-1 mRNA levels in both resting and TPA-treated monocytes. Cycloheximide colony stimulating factor 1 Homo sapiens
4 Moreover, treatment of monocytes with CHX and actinomycin D demonstrated that inhibition of protein synthesis is associated with stabilization of the CSF-1 transcript. Cycloheximide colony stimulating factor 1 Homo sapiens