Title : An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells.

Pub. Date : 2020 Jul 14

PMID : 32640259






1 Functional Relationships(s)
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1 RHOA mutations in cancer cells activated the PI3K-AKT-mTOR signaling pathway, increasing production of free fatty acids that are more effectively consumed by Treg cells than effector T cells. Fatty Acids, Nonesterified mechanistic target of rapamycin kinase Homo sapiens