Title : The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis.

Pub. Date : 2020 Oct

PMID : 32638182






2 Functional Relationships(s)
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1 Treatment of erythrocytes with costunolide dose-dependently enhanced the percentage of annexin-V-binding cells, decreased the cell volume, depleted [GSH]i and completely inhibited G6PDH activity. costunolide annexin A5 Homo sapiens
2 The effects of costunolide on annexin-V-binding and cell volume were significantly reversed by pre-treatment of erythrocytes with the specific PKC-alpha inhibitor chelerythrine. costunolide annexin A5 Homo sapiens