Pub. Date : 2020 Aug 21
PMID : 32636302
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our previous data further showed that the E62K mutation impairs GAP activity for RAC2E62K As this disease mutation is also found in RAS GTPases, we assessed GAP-stimulated GTP hydrolysis for KRAS and observed a similar impairment, suggesting the mutation plays a conserved role in GAP activation. | Guanosine Triphosphate | KRAS proto-oncogene, GTPase | Homo sapiens |