Title : ELT-2 promotes O-GlcNAc transferase OGT-1 expression to modulate Caenorhabditis elegans lifespan.

Pub. Date : 2020 Jul 6

PMID : 32628333






1 Functional Relationships(s)
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1 As UDP-GlcNAc is the final product of the nutrient-sensing hexosamine signaling pathway, overexpression or knockout of ogt in mammals or invertebrate models influences cellular nutrient-response signals and increases susceptibility to chronic diseases of aging. Hexosamines O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens