Title : Intra-articular delivery of flurbiprofen sustained release thermogel: improved therapeutic outcome of collagenase II-induced rat knee osteoarthritis.

Pub. Date : 2020 Dec

PMID : 32627602






2 Functional Relationships(s)
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1 The inflammatory response was attenuated in the samples of flurbiprofen gel treated group by showing decreased IL-1, IL-6, and IL-11 levels in the joint fluid and down-regulated IL-1, IL-6, IL-11, COX-2, TNF-alpha, and NF-kappaB/p65 expression in the articular cartilages. Flurbiprofen interleukin 6 Rattus norvegicus
2 The inflammatory response was attenuated in the samples of flurbiprofen gel treated group by showing decreased IL-1, IL-6, and IL-11 levels in the joint fluid and down-regulated IL-1, IL-6, IL-11, COX-2, TNF-alpha, and NF-kappaB/p65 expression in the articular cartilages. Flurbiprofen interleukin 6 Rattus norvegicus