Title : Impact of DPYD, DPYS, and UPB1 gene variations on severe drug-related toxicity in patients with cancer.

Pub. Date : 2020 Sep

PMID : 32619063






1 Functional Relationships(s)
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1 Cancer treatment with a fluoropyrimidine (FP) is often accompanied by severe toxicity that may be dependent on the activity of catalytic enzymes encoded by the DPYD, DPYS, and UPB1 genes. fp dihydropyrimidine dehydrogenase Homo sapiens