Title : MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3+ regulatory T cells.

Pub. Date : 2020 Dec

PMID : 32612106






1 Functional Relationships(s)
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1 However, there are two distinct isoforms of MCL-1; one located at the outer mitochondrial membrane (OMM) that is required to antagonize apoptosis, and another at the inner mitochondrial membrane (IMM) that is reported to maintain IMM structure and metabolism via ATP production during oxidative phosphorylation. Adenosine Triphosphate MCL1 apoptosis regulator, BCL2 family member Homo sapiens