Title : Thrombin and histamine activate phospholipase C in human endothelial cells via a phorbol ester-sensitive pathway.

Pub. Date : 1988 Jul

PMID : 3260903






1 Functional Relationships(s)
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1 In [3H]myoinositol-labeled cells, both thrombin (3 U/ml)- and histamine (10(-4) M)-induced IP3 increases (195% +/- 6% and 98% +/- 4%, respectively) occurred in less than 15 sec and were temporally correlated with [Ca2+]i increases. Inositol coagulation factor II, thrombin Homo sapiens