Title : A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.

Pub. Date : 2020 Jun 23

PMID : 32607511






1 Functional Relationships(s)
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1 When tested against this reporter virus, remdesivir exhibited substantially more potent activity in A549-hACE2 cells compared to Vero E6 cells (EC 50 0.115 vs 1.28 muM), while this difference was not observed for chloroquine (EC 50 1.32 vs 3.52 muM), underscoring the importance of selecting appropriate cells for antiviral testing. remdesivir angiotensin converting enzyme 2 Homo sapiens