Title : Redox Regulation of NOX Isoforms on FAK(Y397)/SRC(Y416) Phosphorylation Driven Epithelial-to-Mesenchymal Transition in Malignant Cervical Epithelial Cells.

Pub. Date : 2020 Jun 26

PMID : 32604782






1 Functional Relationships(s)
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1 Upon silencing NOX2/4 gene expression and using the SRC inhibitor (AZD0530), progression of TGF-beta1 induced EMT related cellular remodeling, extra cellular matrix (ECM) production, cell migration and invasion, got significantly reverted. saracatinib SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens