Title : Niclosamide and its derivative DK-520 inhibit RANKL-induced osteoclastogenesis.

Pub. Date : 2020 Aug

PMID : 32602250






2 Functional Relationships(s)
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Protein Name
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1 Niclosamide and its derivative DK-520 inhibit RANKL-induced osteoclastogenesis. Niclosamide TNF superfamily member 11 Homo sapiens
2 Treatment with either Niclosamide or DK-520 did not affect the viability of osteoclast precursors (OCPs), but significantly inhibited RANKL-induced trans-differentiation of macrophages into OCPs, particularly in the early stage of osteoclastogenesis. Niclosamide TNF superfamily member 11 Homo sapiens