Pub. Date : 2020 Sep
PMID : 32592718
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ketamine produced a nonsignificant increase in BDNF expression at 1-h but produced a larger, significant (2.2-fold) increase at 24-h in DFP rats. | Ketamine | brain-derived neurotrophic factor | Rattus norvegicus |
| 2 | Ketamine-treated DFP rats exhibited significantly lower [Ca2+]i at 1-h but not at 24-h. Interestingly, treatment with ANA-12, a TrkB-BDNF receptor antagonist, in DFP rats blunted ketamine"s antidepressant-like effect at 24-h but not at 1-h. | Ketamine | brain-derived neurotrophic factor | Rattus norvegicus |