Pub. Date : 2020 Sep
PMID : 32587096
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The first goal of this study was to explore the role of hepatic uptake transporters and characterize transport kinetics of glucuronides of testosterone (TG), dihydrotestosterone (DHTG), androsterone (AG), and etiocholanolone (EtioG) using cell lines overexpressing organic anion transporting polypeptides (OATP1B1, OATP1B3, and OATP2B1). | Glucuronides | solute carrier organic anion transporter family member 1B3 | Homo sapiens |
| 2 | The transport screening assays revealed that the glucuronides were primarily taken up by OATP1B1 and OATP1B3. | Glucuronides | solute carrier organic anion transporter family member 1B3 | Homo sapiens |
| 3 | Both OATP1B1 and OATP1B3 exhibited the highest transport rate toward AG as compared with other glucuronides. | Glucuronides | solute carrier organic anion transporter family member 1B3 | Homo sapiens |