Title : Subsets of acetylcholine-stimulated 86Rb+ efflux and [125I]-epibatidine binding sites in C57BL/6 mouse brain are differentially affected by chronic nicotine treatment.

Pub. Date : 2004 Jun

PMID : 32585787






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 As anticipated, likely alpha4beta2-nAChR [125I]-epibatidine binding sites increased with treatment (estimated dosage for one-half maximal increase was 0.44 mg/kg/h, plasma nicotine 20 ng/ml). epibatidine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 86Rb+ efflux with higher sensitivity to acetylcholine and cytisine-sensitive [125I]-epibatidine binding are predominantly alpha4beta2-nAChR. epibatidine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus