Title : Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion.

Pub. Date : 2020

PMID : 32581761






3 Functional Relationships(s)
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1 Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-kappaB Signaling in Chronic Cerebral Hypoperfusion. 3-n-butylphthalide sirtuin 1 Rattus norvegicus
2 Additionally, NBP induced the activation of AMPK/SIRT1 signaling while inhibiting the STAT3/NF-kappaB pathway. 3-n-butylphthalide sirtuin 1 Rattus norvegicus
3 These results indicate that NBP alleviates cognitive impairment following CCH by promoting remyelination and suppressing inflammation via modulation of AMPK/SIRT1 and STAT3/NF-kappaB signaling. 3-n-butylphthalide sirtuin 1 Rattus norvegicus