Title : Low serum 25-hydroxyvitamin D levels are associated with liver injury markers in the US adult population.

Pub. Date : 2020 Nov

PMID : 32576302






4 Functional Relationships(s)
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1 Multivariate logistic regression and linear regression were applied to assess the associations between serum 25(OH)D levels and ALT, AST, ALP and GGT concentrations. 25(oh)d alkaline phosphatase, placental Homo sapiens
2 RESULTS: We found a significant association between low serum 25(OH)D levels (<30 nmol/l) and ALP levels in all participants (OR 2 67; 95 % CI 1 98, 3 59; P < 0 001), a confirmed healthy population (OR 3 02; 95 % CI 2 25, 4 07; P < 0 001) and individuals with viral hepatitis (OR 2 87; 95 % CI 1 52, 5 44; P = 0 006) compared with those who had normal 25(OH)D levels (>50 nmol/l). 25(oh)d alkaline phosphatase, placental Homo sapiens
3 RESULTS: We found a significant association between low serum 25(OH)D levels (<30 nmol/l) and ALP levels in all participants (OR 2 67; 95 % CI 1 98, 3 59; P < 0 001), a confirmed healthy population (OR 3 02; 95 % CI 2 25, 4 07; P < 0 001) and individuals with viral hepatitis (OR 2 87; 95 % CI 1 52, 5 44; P = 0 006) compared with those who had normal 25(OH)D levels (>50 nmol/l). 25(oh)d alkaline phosphatase, placental Homo sapiens
4 Moreover, in both the logistic regression and linear regression, the associations between 25(OH)D levels and ALP levels were stronger in the subgroups with obesity. 25(oh)d alkaline phosphatase, placental Homo sapiens