Title : Soy isoflavones ameliorate experimental colitis by targeting ERα/NLRP3 inflammasome pathways.

Pub. Date : 2020 Sep

PMID : 32563803






1 Functional Relationships(s)
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1 Our study demonstrated that the protective therapeutic action of SIFs on DSS-induced colitis depended on inhibition of ERalpha and subsequent NLRP3 inflammasome activation, and SIFs are promising therapeutic agents for the treatment of colitis. dss NLR family, pyrin domain containing 3 Mus musculus