Title : COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status.

Pub. Date : 2020 Jul 23

PMID : 32559180






1 Functional Relationships(s)
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1 Interestingly, metabolite levels in these pathways correlated with clinical laboratory markers of inflammation (i.e., IL-6 and C-reactive protein) and renal function (i.e., blood urea nitrogen).CONCLUSIONIn conclusion, this initial observational study identified amino acid and fatty acid metabolism as correlates of COVID-19, providing mechanistic insights, potential markers of clinical severity, and potential therapeutic targets.FUNDINGBoettcher Foundation Webb-Waring Biomedical Research Award; National Institute of General and Medical Sciences, NIH; and National Heart, Lung, and Blood Institute, NIH. Fatty Acids interleukin 6 Homo sapiens