Pub. Date : 2020 Aug
PMID : 32554208
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated the involvement of klotho in the inhibition of oxidative stress by sodium butyrate (NaB) in human nucleus pulposus cells (NPCs). | nab | klotho | Homo sapiens |
| 2 | Intriguingly, NaB significantly reversed TBHP-induced klotho suppression. | nab | klotho | Homo sapiens |
| 3 | However, the protective effects of NaB on NPCs were abolished by klotho-specific small interfering RNA (siRNA). | nab | klotho | Homo sapiens |
| 4 | Therefore, NaB alleviates TBHP-induced oxidative stress in human NPCs by elevating PPARgamma-regulated klotho expression. | nab | klotho | Homo sapiens |