| Protein Name | klotho |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 9365 |
| Gene Symbol | KL |
| UniProt | Q9UEF7 (KLOT_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
224
Total Number of Articles : 414 |
Description |
klotho |
| Gene Summary |
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008] |
| synonyms |
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| Properties | |