Title : Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARĪ³1.

Pub. Date : 2020 Aug 15

PMID : 32553810






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1 Furthermore, through western blotting analysis lycopene intervention was found to have significantly improved apoptosis cytokines by increasing the protein expression levels of PPARgamma and caspase-3, and also significantly reduced inflammatory cytokines by decreasing the protein expression of NF-kappaB and COX-2 in the esophagus tissue, especially in the 25 mg/kg of lycopene intervention group (all P < 0.05). Lycopene peroxisome proliferator-activated receptor gamma Rattus norvegicus