Pub. Date : 2021 Jan
PMID : 32553670
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The selective PPAR-delta agonist seladelpar reduces ethanol-induced liver disease by restoring gut barrier function and bile acid homeostasis in mice. | Seladelpar | peroxisome proliferator activator receptor delta | Mus musculus |
| 2 | Here, we evaluated the effect of the selective PPAR-delta agonist seladelpar (MBX-8025) on gut barrier function and bile acid metabolism in a mouse model of ethanol-induced liver disease. | Seladelpar | peroxisome proliferator activator receptor delta | Mus musculus |
| 3 | Data from this study demonstrates that seladelpar prevents and treats ethanol-induced liver damage in mice by direct PPARdelta agonism in both the liver and the intestine. | Seladelpar | peroxisome proliferator activator receptor delta | Mus musculus |