| Protein Name | peroxisome proliferator activator receptor delta |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19015 |
| Gene Symbol | Ppard |
| UniProt | P35396 (PPARD_MOUSE), Q546I3 (Q546I3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
269
Total Number of Articles : 373 |
Description |
peroxisome proliferator activator receptor delta |
| Gene Summary |
Enables DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in several processes, including negative regulation of myoblast differentiation; positive regulation of skeletal muscle tissue regeneration; and regulation of gene expression. Acts upstream of or within several processes, including keratinocyte migration; keratinocyte proliferation; and positive regulation of phosphatidylinositol 3-kinase signaling. Located in chromatin and nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Used to study Huntington's disease and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022] |
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