Title : Inhibition of NK1R attenuates LPS-induced microglial inflammation and consequent death of PC12 cells.

Pub. Date : 2020 Sep

PMID : 32540418






1 Functional Relationships(s)
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1 Application of CP-99994, a selective antagonist of NK1R, inhibited the production of inflammatory mediators such as tumor necrosis factor-alpha (TNF-alpha), interleukin 1 beta (IL-1beta), IL-6, inducible macrophage-type nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) in activated BV2 cells. 3-(2-methoxybenzylamino)-2-phenylpiperidine interleukin 6 Mus musculus