Pub. Date : 2020 Oct 1
PMID : 32534005
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Roxadustat ameliorated pulmonary fibrosis by reducing the pathology score and collagen deposition as well as decreasing the expression of collagen I, collagen III, PHD2, HIF-1alpha, alpha-SMA, CTGF, TGF-beta1 and p-Smad3/Smad3. | roxadustat | transforming growth factor, beta 1 | Mus musculus |
| 2 | Our cumulative results demonstrate that roxadustat administration can attenuate experimental pulmonary fibrosis via the inhibition of TGF-beta1/Smad activation. | roxadustat | transforming growth factor, beta 1 | Mus musculus |