Title : HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling.

Pub. Date : 2020 Nov

PMID : 32519137






2 Functional Relationships(s)
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1 We showed that HTR2A knockdown repressed ISO-induced cardiomyocyte hypertrophy, which was demonstrated by decreased cardiomyocyte size and repressed expression of hypertrophic fetal genes (e.g., myosin heavy chain beta (beta-Mhc), atrial natriuretic peptide (Anp), and brain natriuretic peptide (Bnp)). Isoproterenol natriuretic peptide B Homo sapiens
2 We showed that HTR2A knockdown repressed ISO-induced cardiomyocyte hypertrophy, which was demonstrated by decreased cardiomyocyte size and repressed expression of hypertrophic fetal genes (e.g., myosin heavy chain beta (beta-Mhc), atrial natriuretic peptide (Anp), and brain natriuretic peptide (Bnp)). Isoproterenol natriuretic peptide B Homo sapiens