Title : The Migratory Properties and Numbers of T Regulatory Cell Subsets in Circulation Are Differentially Influenced by Season and Are Associated With Vitamin D Status.

Pub. Date : 2020

PMID : 32508805






2 Functional Relationships(s)
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1 Some nTreg variation could be attributed to vitamin D status where normal linear regression estimated that an absolute increase in nTreg/CD4+ by 0.11% could be expected with 10 nmol increase in serum 25 (OH) vitamin D3 (p = 0.005, 95% CI: 0.03-0.19). Cholecalciferol CD4 molecule Homo sapiens
2 Important for cellular therapies requiring isolation of Tregs, the absolute number of beta7+CD4+CD25+FOXP3+Tregs was positively associated with 25(OH)vitamin D3 (R 2 = 0.0208, r = 0.184, p = 0.021) whereas the absolute numbers of CLA+CD4+CD25+FOXP3+Tregs in the periphery were not influenced by vitamin D status. Cholecalciferol CD4 molecule Homo sapiens