Title : PNU282987 alleviates Aβ-induced anxiety and depressive-like behaviors through upregulation of α7nAChR by ERK-serotonin receptors pathway.

Pub. Date : 2020 Jul 13

PMID : 32502508






2 Functional Relationships(s)
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1 PNU282987 alleviates Abeta-induced anxiety and depressive-like behaviors through upregulation of alpha7nAChR by ERK-serotonin receptors pathway. Serotonin cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Our study provides a new insight into the mechanism of alpha7nAChR in Abeta-induced depression and anxiety-related symptoms through the regulation of ERK1/2 pathway and the potential association with serotonin receptors. Serotonin cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus