Title : Peripheral Expression of CXCL10 Gene in Chronic Hepatitis C Patients Treated with Sofosbuvir, Daclatasvir, and Ribavirin.

Pub. Date : 2020 Jun

PMID : 32486887






5 Functional Relationships(s)
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1 Peripheral Expression of CXCL10 Gene in Chronic Hepatitis C Patients Treated with Sofosbuvir, Daclatasvir, and Ribavirin. Ribavirin C-X-C motif chemokine ligand 10 Homo sapiens
2 This study aimed to examine the expression level of C-X-C motif chemokine ligand 10 (CXCL10) in the Peripheral blood mononuclear cells (PBMCs) of HCV infected patients treated with DAAs + Ribavirin. Ribavirin C-X-C motif chemokine ligand 10 Homo sapiens
3 This study aimed to examine the expression level of C-X-C motif chemokine ligand 10 (CXCL10) in the Peripheral blood mononuclear cells (PBMCs) of HCV infected patients treated with DAAs + Ribavirin. Ribavirin C-X-C motif chemokine ligand 10 Homo sapiens
4 In this study we analyzed the expression levels of CXCL10 mRNA in the 90 chronic HCV patients using quantitative PCR (qPCR) prior, after, and during therapy with sofosbuvir/ribavirin (SOF+RBV) and sofosbuvir/daclatasvir/ribavirin (SOF+DCV+RBV), and further, the results were analyzed relative to treatment response. Ribavirin C-X-C motif chemokine ligand 10 Homo sapiens
5 Comparing the 2 regimens, the reduction in peripheral CXCL10 expression was more pronounced in patients undergoing SOF+DCV+RBV therapy. Ribavirin C-X-C motif chemokine ligand 10 Homo sapiens