Title : Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight.

Pub. Date : 2020 May 29

PMID : 32485818






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NU172-a 26-mer oligonucleotide able to bind exosite I of human thrombin and inhibit its activity-was the first aptamer to reach Phase II clinical studies as an anticoagulant in heart disease treatments. Oligonucleotides coagulation factor II, thrombin Homo sapiens