Title : Significant reduction of apoptosis induced via hypoxia and oxidative stress in isolated human islet by resveratrol.

Pub. Date : 2020 Jun 25

PMID : 32482454






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1 This insult induced apoptosis and decreased viability during 72 h. The presence of resveratrol significantly attenuated HIF-1alpha and ROS production, reduced apoptosis, promoted the VEGF secretion, and increased the insulin and C-peptide secretion. Resveratrol hypoxia inducible factor 1 subunit alpha Homo sapiens