Pub. Date : 2020
PMID : 32477105
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-kappaB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-kappaB Pathway in Adjuvant-Induced Arthritis. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 2 | Furthermore, this reduction in NLRP3 inflammasome activation was also associated with decreases in the activation of nuclear factor (NF-kappaB), the production of reactive oxygen species (ROS), and the expression of inflammatory IL-6. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 3 | Furthermore, this reduction in NLRP3 inflammasome activation was also associated with decreases in the activation of nuclear factor (NF-kappaB), the production of reactive oxygen species (ROS), and the expression of inflammatory IL-6. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |
| 4 | Together these findings indicate that Gent can suppress the ROS-NF-kappaB-NLRP3 axis to alleviate RA symptoms. | Reactive Oxygen Species | NLR family, pyrin domain containing 3 | Rattus norvegicus |