Pub. Date : 2020 Dec
PMID : 32475982
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Subtherapeutic bupropion and hydroxybupropion serum concentrations in a patient with CYP2C19*1/*17 genotype suggesting a rapid metabolizer status. | Bupropion | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 2 | The present case shows a reduced bupropion efficacy, which may be explained by a reduced active moiety of bupropion and its active metabolite hydroxybupropion, due to alternative hydroxylation pathways mediated by CYP2C19 in an individual with CYP2C19 rapid metabolizer status. | Bupropion | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 3 | The present case shows a reduced bupropion efficacy, which may be explained by a reduced active moiety of bupropion and its active metabolite hydroxybupropion, due to alternative hydroxylation pathways mediated by CYP2C19 in an individual with CYP2C19 rapid metabolizer status. | Bupropion | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 4 | The present case shows a reduced bupropion efficacy, which may be explained by a reduced active moiety of bupropion and its active metabolite hydroxybupropion, due to alternative hydroxylation pathways mediated by CYP2C19 in an individual with CYP2C19 rapid metabolizer status. | Bupropion | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |
| 5 | The present case shows a reduced bupropion efficacy, which may be explained by a reduced active moiety of bupropion and its active metabolite hydroxybupropion, due to alternative hydroxylation pathways mediated by CYP2C19 in an individual with CYP2C19 rapid metabolizer status. | Bupropion | cytochrome P450 family 2 subfamily C member 19 | Homo sapiens |