Pub. Date : 2020 Jul 31
PMID : 32475820
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mice receiving thiamet G (TMG), an inhibitor of the O-GlcNAc hydrolase O-GlcNAcase, exhibited enhanced retinal protein O-GlcNAcylation and increased Cd40 mRNA translation. | thiamet G | CD40 antigen | Mus musculus |
| 2 | Mice receiving thiamet G (TMG), an inhibitor of the O-GlcNAc hydrolase O-GlcNAcase, exhibited enhanced retinal protein O-GlcNAcylation and increased Cd40 mRNA translation. | thiamet G | CD40 antigen | Mus musculus |
| 3 | TMG administration also promoted Cd40 mRNA association with Muller cell-specific ribosomes isolated from the retina of RiboTag mice. | thiamet G | CD40 antigen | Mus musculus |
| 4 | In cultured cells, TMG promoted sequestration of the cap-binding protein eIF4E (eukaryotic translation in initiation factor 4E) by 4E-BP1 (eIF4E-binding protein 1) and enhanced cap-independent Cd40 mRNA translation as assessed by a bicistronic reporter that contained the 5"-UTR of the Cd40 mRNA. | thiamet G | CD40 antigen | Mus musculus |
| 5 | In cultured cells, TMG promoted sequestration of the cap-binding protein eIF4E (eukaryotic translation in initiation factor 4E) by 4E-BP1 (eIF4E-binding protein 1) and enhanced cap-independent Cd40 mRNA translation as assessed by a bicistronic reporter that contained the 5"-UTR of the Cd40 mRNA. | thiamet G | CD40 antigen | Mus musculus |